The child of a police officer father and a dedicated mother, Miles struggles to adapt to his new school. His parents wish to see the success of their son who goes to a private school for only talented students. However, Miles has little to do with school. He mostly wants to spend time with his friends and uncle Aaron, who encourages him about graffiti. While Miles struggles with minor problems in his life, he steps into a completely different world as he is bitten by a radioactive spider. He is now a superhero with special abilities. Gaining to many special powers such as poison throwing, camouflage, sticking to objects and very advanced hearing, Miles gets help from Peter Parker, Spider-Gwen, Spider-Man Noir, Spider-Ham to become a true superhero. After learning the responsibilities of being a superhero, Miles should now take action to put on his mask and fight the evil.